Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimagedine SCHEMBL7763659 | 1.00 | ALDH1A1 (0.43) | ALDH1A1PTGS2HSD17B10CYP1A2TSHR | |
| Pimagedine SCHEMBL15307 | 1.00 | — | — | |
| Pimagedine SCHEMBL9716859 | 0.95 | — | — | |
| Pimagedine SCHEMBL10340639 | 0.95 | ALDH1A1 (0.40) | ALDH1A1PTGS2HSD17B10CYP1A2TSHR | |
| Pimagedine SCHEMBL9734994 | 0.95 | — | — | |
| Pimagedine SCHEMBL23779762 | 0.95 | — | — | |
| Pimagedine SCHEMBL3818920 | 0.95 | — | — | |
| Pimagedine SCHEMBL19122 | 0.95 | — | — | |
| Pimagedine SCHEMBL1724778 | 0.95 | ALDH1A1 (0.40) | ALDH1A1PTGS2HSD17B10CYP1A2TSHR | |
| Pimagedine SCHEMBL8446446 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109806276-A | Lentinan prevents the application in diabetes complicated disease drug in preparation | 辽宁大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-109053580-A | A kind of synthetic method of cosmetics dipeptides | 湖北泓肽生物科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-106232085-A | Microcapsules containing colorants | 塔格拉生物技术有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-105163706-A | Microcapsules comprising sunscreen agents | TAGRA BIOTECHNOLOGIES LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-1097580-C | Aminoguanidine carboxylates for the treatment of non-insulin dependent diabetes mellitus | BIOVITRUM AB (SE) | 2003-01-01 | — | — | CN | disclosed |
| CN-1377642-A | Use of compound for preparing medicine for curing and preventing non-insulin dependent diabetes or obesity | BIOVITRUM AB (SE) | 2002-11-06 | — | — | CN | disclosed |
| CN-1164226-A | Aminoguanidine carboxylates for the treatment of non-insulin dependent diabetes mellitus | UPJOHN CO (US) | 1997-11-05 | — | — | CN | disclosed |
| CN-1055063-A | The analysis of aminoguanidine and application thereof | GERITECH INC (US) | 1991-10-02 | — | — | CN | disclosed |