Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pimagedine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimagedine SCHEMBL5974216 | 1.00 | LMNA (0.47) | — | |
| Pimagedine SCHEMBL8446446 | 1.00 | — | — | |
| Pimagedine SCHEMBL4915673 | 1.00 | — | — | |
| Pimagedine SCHEMBL8341879 | 1.00 | LMNA (0.47) | — | |
| Pimagedine SCHEMBL27633636 | 0.96 | LMNA (0.44) | — | |
| Pimagedine SCHEMBL2411461 | 0.96 | — | — | |
| Pimagedine SCHEMBL28756552 | 0.96 | — | — | |
| Pimagedine SCHEMBL15307 | 0.95 | — | — | |
| Pimagedine SCHEMBL27366958 | 0.95 | ALDH1A1 (0.43) | — | |
| Pimagedine SCHEMBL7763659 | 0.95 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2794 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260107679-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIV ARIZONA STATE (US) | 2026-04-16 | — | — | US | claimed |
| EP-4719593-A1 | ENANTIOSELECTIVE PREPARATION METHOD | Immunahr AB (SE) | 2026-04-08 | — | — | EP | claimed |
| US-20260085084-A1 | Judicious Design of Benzo-carbene Based Metal Complex Emitters For Fast Radiative Organic Light Emitting Diodes | UNIV ARIZONA STATE (US) | 2026-03-26 | — | — | US | claimed |
| US-20250374821-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIV ARIZONA STATE (US) | 2025-12-04 | — | — | US | claimed |
| EP-4640204-A2 | HAIR COSMETIC COMPOSITION | Kao Corporation (JP) | 2025-10-29 | — | — | EP | claimed |
| EP-3831362-B1 | HAIR COSMETIC COMPOSITION | KAO CORP (JP) | 2025-10-15 | — | — | EP | claimed |
| US-20250277207-A1 | One or Multiple-Steps Extraction of Nucleic Acids and other Biomolecules using a Cloudy Precipitated Solution | CHHALLIYIL PRADHEEP (US) | 2025-09-04 | — | — | US | claimed |
| US-20250223163-A1 | CARBON NITRIDES WITH HIGHLY CRYSTALLINE FRAMEWORK AND PROCESS FOR PRODUCING SAME | THE UNIVERSITY OF NEWCASTLE (AU) | 2025-07-10 | — | — | US | claimed |
| US-20250188344-A1 | Tetradentate Platinum And Palladium Complex Emitters | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2025-06-12 | — | — | US | claimed |
| EP-4565367-A1 | CARBON NITRIDES WITH HIGHLY CRYSTALLINE FRAMEWORK AND PROCESS FOR PRODUCING SAME | The University of Newcastle (AU) | 2025-06-11 | — | — | EP | claimed |
| US-5424449-A | Reacting aminoguanidine salt of mineral acid with a diazotization agent to form guanylazide salt; cyclization | OLIN CORPORATION (US) | 1995-06-13 | — | — | US | claimed |
| EP-0636023-A1 | AMINOGUANIDINE SPRAY DRYING PROCESS | HOECHST MARION ROUSSEL, INC. (US) | 1995-02-01 | — | — | EP | claimed |
| EP-0283876-B1 | Substituted triazolinones | BAYER AG (DE) | 1994-07-20 | — | — | EP | claimed |
| WO-1993020808-A1 | AMINOGUANIDINE SPRAY DRYING PROCESS | MARION MERRELL DOW INC. (US) | 1993-10-28 | — | — | WO | claimed |
| US-5128360-A | Inhibition of advanced glycosylation end products of target proteins using aminoguanidine and-or hydrazinohistidine | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | claimed |
| EP-0448228-A2 | Aminoguanidine assay and applications thereof | ALTEON INC. (US) | 1991-09-25 | — | — | EP | claimed |
| EP-0305844-A1 | Substituted triazolinones | BAYER AG (DE) | 1989-03-08 | — | — | EP | claimed |
| EP-0283876-A2 | Substituted triazolinones | BAYER AG (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4149980-A | AMINOGUANIDINE SULFONATE OVERBASED COMPOUND | STANDARD OIL COMPANY (INDIANA) (US) | 1979-04-17 | — | — | US | claimed |
| US-3941825-A | ANTIPROTOZOA INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1976-03-02 | — | — | US | claimed |