Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL3791448 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL8463 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Benzene SCHEMBL6754211 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2468018 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Phosphine SCHEMBL29048968 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2342230 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28811288 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5731497 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL3230271 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Methane SCHEMBL9326425 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986857-B | Trk inhibiting compound | 小野药品工业株式会社 | 2019-07-05 | — | — | CN | disclosed |
| CN-106986857-A | Trk inhibiting compounds | 小野药品工业株式会社 | 2017-07-28 | — | — | CN | disclosed |
| CN-106928197-A | Trk inhibiting compounds | 小野药品工业株式会社 | 2017-07-07 | — | — | CN | disclosed |
| CN-104995172-B | Trk inhibiting compounds | 小野药品工业株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-104136525-A | Propylene-ethylene copolymer resin composition, and molded product, film and sheet thereof | JAPAN POLYPROPYLENE CORP | 2014-11-05 | — | — | CN | disclosed |
| CN-1260257-C | Catalyst for olefin polymerization and method for polymerization of olefin | JAPAN POLYCHEM CORP (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1232546-C | Modified propylene polymer, composition containing the same and use thereof | MITSUBISHI CHEM IND (JP) | 2005-12-21 | — | — | CN | disclosed |
| CN-1680453-A | Modified propylene polymer, composition containing the same and use thereof | MITSUBISHI CHEM CORP (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1520426-A | Catalyst for olefin polymerization and method for polymerization of olefin | �ձ��۱�ϩ��˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1417236-A | Modified propylene polymer, composition containing the same and use thereof | MITSUBISHI CHEM IND (JP) | 2003-05-14 | — | — | CN | disclosed |
| CN-1086707-C | Metallocenes, their preparation and their use for the polymerization of alpha-olefins | ENICHEM SPA (IT) | 2002-06-26 | — | — | CN | disclosed |
| CN-1301154-A | Amide derivatives and nociceptin antagonists | JAPAN TOBACCO INC (JP) | 2001-06-27 | — | — | CN | disclosed |
| CN-1066736-C | Bridged cyclopentadienyl derivatives and process for their preparation | ENICHEM SPA (IT) | 2001-06-06 | — | — | CN | disclosed |
| CN-1153178-A | Bridged cyclopentadienyl derivatives and process for their preparation | ENICHEM SPA (IT) | 1997-07-02 | — | — | CN | disclosed |