Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10622486 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL29185389 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Benzene SCHEMBL6754211 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2468018 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL1198500 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL8463 | 0.95 | ALDH1A1 (0.90) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5731497 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Methane SCHEMBL9326425 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28811288 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 | |
| Biphenyl SCHEMBL2722776 | 0.91 | ALDH1A1 (0.82) | ALDH1A1TAAR1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376382-B2 | N-substituted isopropyldimethyl azulene sulfonamide derivatives, and preparation method and use thereof | SICHUAN GUOKANG PHARMACEUTICAL CO., LTD. (CN) | 2016-06-28 | — | — | US | claimed |
| CN-103385863-B | Sodium azulene sulfonate sustained-release preparation | Sichuan guokang pharmaceutical co ltd | 2015-07-15 | — | — | CN | claimed |
| US-20140206741-A1 | N-SUBSTITUTED ISOPROPYLDIMETHYL AZULENE SULFONAMIDE DERIVATIVES, AND PREPARATION METHOD AND USE THEREOF | SICHUAN GUOKANG PHARMACEUTICAL CO., LTD (CN) | 2014-07-24 | — | — | US | claimed |
| US-8263125-B2 | Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| JP-11302196-A | — | — | None | — | — | JP | disclosed |
| JP-11302196-A | — | — | None | — | — | JP | disclosed |
| US-20250228887-A1 | OPHTHALMIC COMPOSITION | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2025-07-17 | — | — | US | disclosed |
| CN-120053302-A | Oral composition | 狮王株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-120053301-A | Oral composition | 狮王株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-120053299-A | Oral composition | 狮王株式会社 | 2025-05-30 | — | — | CN | disclosed |
| US-12161652-B2 | Anionic drug-containing ophthalmic device | SEED CO., LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| CN-119015243-A | Preparation method of sodium azulene sulfonate tablet with stable storage and long-acting release | 山东华素制药有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-103385863-A | Sodium azulene sulfonate sustained-release preparation | Sichuan guokang pharmaceutical co ltd | 2013-11-13 | — | — | CN | disclosed |
| CN-103385863-A | Sodium azulene sulfonate sustained-release preparation | Sichuan guokang pharmaceutical co ltd | 2013-11-13 | — | — | CN | disclosed |
| US-20100069323-A1 | COMPOSITION FOR APPLICATION TO SKIN OR MUCOSA | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| CN-1561986-A | Capsule agent containing L-glutamine and azulene sodium solfonate | ZHANG HONGJUN (CN) | 2005-01-12 | — | — | CN | disclosed |
| JP-H11302196-A | SODIUM AZULENE SULFONATE-CONTAINING PREPARATION | SUMITOMO PHARMACEUT CO LTD | 1999-11-02 | — | — | JP | disclosed |
| JP-H11302196-A | SODIUM AZULENE SULFONATE-CONTAINING PREPARATION | SUMITOMO PHARMACEUT CO LTD | 1999-11-02 | — | — | JP | disclosed |
| EP-0147915-B1 | NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS | Kotobuki Seiyaku Co., Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |
| EP-0147915-A1 | New azulene derivatives useful as anti-ulcerative and anti-flammatory agents | Kotobuki Seiyaku Co., Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206741-A1 | N-SUBSTITUTED ISOPROPYLDIMETHYL AZULENE SULFONAMIDE DERIVATIVES, AND PREPARATION METHOD AND USE THEREOF | GIPR, SSTR5, STS | ALDH1A1 244/4885TAAR1 901/4885MAPK1 3525/4885 |
| US-12161652-B2 | Anionic drug-containing ophthalmic device | ACMSD, UACA, ADSL | ALDH1A1 2770/4885TAAR1 1261/4885MAPK1 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.