Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367223 | 0.82 | AKR1C3 (0.39) | AKR1C3AKR1C2GAAAOC3SMN1; SMN2 | |
| SCHEMBL13933868 | 0.75 | CYP2D6 (0.53) | MEN1KMT2ATSHRAOC3 | |
| SCHEMBL9696473 | 0.73 | AKR1C3 (0.60) | AKR1C3AKR1C2TSHRMAPT | |
| SCHEMBL5151171 | 0.71 | MEN1 (0.53) | MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29700742 | 0.70 | AOC3 (0.59) | MEN1KMT2ATSHRAOC3 | |
| SCHEMBL29212110 | 0.69 | NPC1 (0.61) | MEN1KMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29964126 | 0.69 | NPC1 (0.61) | MEN1KMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3881897 | 0.66 | MAPT (0.51) | MEN1KMT2AGAANPC1SMN1; SMN2 | |
| SCHEMBL11437881 | 0.66 | ALDH1A1 (0.50) | MEN1KMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL27367160 | 0.66 | CYP2C9 (0.52) | TSHRGAASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |