Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CDC42 | P60953 | 1/20 | 0.60 |
| ▸ | RAC1 | P63000 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651836 | 0.89 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL60543 | 0.89 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL15782118 | 0.86 | AKR1C3 (0.62) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL4478662 | 0.85 | FFAR1 (0.56) | FFAR1MAPTL3MBTL1 | |
| SCHEMBL4478666 | 0.85 | FFAR1 (0.56) | FFAR1MAPTL3MBTL1 | |
| SCHEMBL3967988 | 0.84 | ABCB11 (0.67) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL8771236 | 0.83 | L3MBTL1 (0.75) | FFAR1LMNAL3MBTL1TDP1 | |
| SCHEMBL7557544 | 0.81 | AKR1C3 (0.64) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| SCHEMBL15782117 | 0.81 | AKR1C3 (0.56) | AKR1C3AKR1C2PTGS1PTGS2TSHR | |
| Naproxen SCHEMBL28556440 | 0.80 | AKR1C3 (0.76) | AKR1C3AKR1C2PTGS1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001062-A1 | PROCESS FOR PRODUCING ENANTIOMERS OF 2-ARYL-ALKANOIC ACIDS | NOVO NORDISK A/S (DK) | 1992-01-23 | — | — | WO | claimed |
| WO-1992001062-A1 | PROCESS FOR PRODUCING ENANTIOMERS OF 2-ARYL-ALKANOIC ACIDS | NOVO NORDISK A/S (DK) | 1992-01-23 | — | — | WO | disclosed |