Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367305 | 0.85 | NPC1 (0.53) | HTTALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL27366954 | 0.84 | KMT2A (0.43) | HTTALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL630214 | 0.81 | DRD2 (0.51) | ALDH1A1SMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL7289390 | 0.81 | DRD2 (0.51) | ALDH1A1SMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL629772 | 0.81 | OPRK1 (0.48) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10528530 | 0.80 | CYP4F2 (0.46) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL10529754 | 0.80 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL21383104 | 0.80 | SHMT2 (0.46) | ALDH1A1POLBLMNAGAAKMT2A | |
| SCHEMBL30437653 | 0.80 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10528366 | 0.79 | SHMT2 (0.45) | ALDH1A1POLBGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |