Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364619 | 0.85 | KMT2A (0.42) | KMT2AMEN1L3MBTL3L3MBTL1MAPT | |
| SCHEMBL27368371 | 0.84 | ADRB1 (0.45) | KMT2AMEN1 | |
| SCHEMBL27366536 | 0.82 | PDE10A (0.43) | KMT2AMEN1MAPT | |
| SCHEMBL27365606 | 0.77 | MAPT (0.44) | KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL27367216 | 0.74 | EBP (0.43) | — | |
| SCHEMBL12082219 | 0.72 | MAPT (0.51) | KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL20372819 | 0.71 | MAPT (0.51) | MAPTNPSR1 | |
| SCHEMBL27365359 | 0.70 | ADRB1 (0.38) | KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL14924468 | 0.70 | KMT2A (0.67) | KMT2AL3MBTL3L3MBTL1MAPT | |
| SCHEMBL81591 | 0.70 | L3MBTL3 (0.57) | KMT2AMEN1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054591-A1 | RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |