SCHEMBL27367436

SCHEMBL27367436

C=C(CCCN(C)CCC)CCOI

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.34
KDM4C Q9H3R0 2/20 0.34
DNM1 Q05193 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25740863 0.81 KDM5A (0.35) KDM5AKDM4CDNM1SIGMAR1
SCHEMBL25147997 0.75 ALDH1A1 (0.38) KDM5AKDM4CDNM1SIGMAR1
SCHEMBL25739503 0.75 MEN1 (0.34) KDM5AKDM4CDNM1
SCHEMBL21078288 0.74 MEN1 (0.36) KDM5AKDM4CDNM1
SCHEMBL25738624 0.74 ALDH1A1 (0.37) KDM5AKDM4CDNM1
SCHEMBL13701208 0.72
SCHEMBL18434533 0.71 KDM4C (0.41) KDM5AKDM4CSIGMAR1
SCHEMBL27413850 0.71 KDM5A (0.35) KDM5AKDM4CSIGMAR1
SCHEMBL22738350 0.70 KDM4C (0.50) KDM5AKDM4CDNM1
SCHEMBL27383432 0.70 KDM4C (0.50) KDM5AKDM4CDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054766-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER MITO BIOPHARMA, LLC (US) 2024-03-14 WO disclosed