Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25739503 | 0.89 | MEN1 (0.34) | MEN1KMT2APIK3CDKDM5AKDM4C | |
| SCHEMBL25738624 | 0.87 | ALDH1A1 (0.37) | MEN1KMT2AKDM5AKDM4CDNM1 | |
| SCHEMBL25740863 | 0.83 | KDM5A (0.35) | KDM5AKDM4CDNM1 | |
| SCHEMBL27413850 | 0.81 | KDM5A (0.35) | MEN1KMT2AKDM5AKDM4C | |
| SCHEMBL24242106 | 0.80 | MEN1 (0.39) | MEN1KMT2AKDM5AKDM4CDNM1 | |
| SCHEMBL7774988 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL25147997 | 0.77 | ALDH1A1 (0.38) | MEN1KMT2AKDM5AKDM4CDNM1 | |
| SCHEMBL735129 | 0.75 | — | — | |
| SCHEMBL23507002 | 0.74 | MAOA (0.31) | — | |
| SCHEMBL27367436 | 0.74 | KDM5A (0.34) | KDM5AKDM4CDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |