Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.37 |
| ▸ | KDM5A | P29375 | 7/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413850 | 0.86 | KDM5A (0.35) | KDM4CKDM5ASIGMAR1MEN1KMT2A | |
| SCHEMBL21698552 | 0.84 | DNM1 (0.44) | ALDH1A1CES2CES1DNM1ALDH2 | |
| SCHEMBL25739503 | 0.82 | MEN1 (0.34) | ALDH1A1KDM4CKDM5AS1PR2S1PR1 | |
| SCHEMBL25738624 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KDM4CKDM5ADNM1MEN1 | |
| SCHEMBL22738350 | 0.80 | KDM4C (0.50) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL27383432 | 0.80 | KDM4C (0.50) | KDM4CKDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL4244087 | 0.80 | CES1 (0.47) | ALDH1A1CES2CES1MEN1KMT2A | |
| SCHEMBL20920844 | 0.78 | KDM5A (0.35) | ALDH1A1KDM4CKDM5AS1PR2S1PR1 | |
| SCHEMBL170759 | 0.77 | DNM1 (0.48) | ALDH1A1CES2CES1DNM1THRA | |
| SCHEMBL4791412 | 0.77 | DNM1 (0.48) | ALDH1A1CES2CES1DNM1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |