Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780319 | 0.84 | DYRK1A (0.42) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL30568075 | 0.84 | DYRK1A (0.42) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL12490214 | 0.83 | MEN1 (0.42) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL2134361 | 0.83 | ALDH1A1 (0.39) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL10830908 | 0.79 | TDP1 (0.42) | TDP1 | |
| SCHEMBL12490313 | 0.78 | DYRK1A (0.41) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL2131306 | 0.78 | DYRK1A (0.41) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL21768190 | 0.78 | DYRK1A (0.41) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL30831844 | 0.78 | DYRK1A (0.41) | DYRK1ATSHRLMNANPC1RAB9A | |
| SCHEMBL28044154 | 0.77 | GABRA1 (0.39) | TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |