Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751084 | 0.76 | HRH3 (0.40) | KDM4EALDH1A1SMN1; SMN2SPHK2SPHK1 | |
| SCHEMBL6590979 | 0.71 | TDP1 (0.37) | KDM4EALDH1A1SMN1; SMN2SPHK2SPHK1 | |
| Phenoxyethanol SCHEMBL28142983 | 0.70 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21695105 | 0.70 | RAB9A (0.57) | ALDH1A1MEN1KMT2AHRH3TMEM97 | |
| SCHEMBL27457708 | 0.69 | SLC18A3 (0.49) | ALDH1A1SMN1; SMN2KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL15939331 | 0.68 | ALDH1A1 (0.57) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Phenoxyethanol SCHEMBL5469246 | 0.68 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2SLC18A3 | |
| SCHEMBL13640459 | 0.68 | KMT2A (0.41) | MEN1KMT2ATMEM97SIGMAR1 | |
| SCHEMBL7111287 | 0.68 | TERT (0.43) | KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL10570038 | 0.67 | SPHK1 (0.49) | KDM4ESPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068597-C | Process for preparing 4 -aryl -piperidine derivatives | NOVO NORDISK AS (DK) | 2001-07-18 | — | — | CN | disclosed |
| CN-1184476-A | Process for preparing 4 -aryl -piperidine derivatives | NOVO NORDISK AS (DK) | 1998-06-10 | — | — | CN | disclosed |