Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032736 | 0.82 | LMNA (0.64) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9031644 | 0.81 | LMNA (0.62) | LMNAKMT2AMEN1GAANPY5R | |
| Hydrochloric Acid SCHEMBL9400516 | 0.81 | LMNA (0.61) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL27350251 | 0.77 | LMNA (0.51) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9032107 | 0.76 | LMNA (0.53) | LMNAKMT2AGAANPY5RALDH1A1 | |
| SCHEMBL15134220 | 0.75 | LMNA (1.00) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL9034666 | 0.75 | LMNA (0.60) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9032683 | 0.74 | HTR7 (0.65) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9030434 | 0.73 | LMNA (0.50) | LMNAKMT2AMEN1GAANPY5R | |
| Hydrochloric Acid SCHEMBL9400405 | 0.73 | HTR7 (0.64) | LMNAKMT2AMEN1GAANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053919-A | New imidazolium compounds, its preparation method and based on medicament and some intermediate product of these compounds | HOECHST AG (DE) | 1991-08-21 | — | — | CN | disclosed |