Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031644 | 0.90 | LMNA (0.62) | LMNAKMT2AMEN1GAANPY5R | |
| Hydrochloric Acid SCHEMBL9400516 | 0.89 | LMNA (0.61) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL27368480 | 0.82 | LMNA (0.59) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9034367 | 0.80 | LMNA (0.53) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL15134220 | 0.79 | LMNA (1.00) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL9034666 | 0.78 | LMNA (0.60) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9032683 | 0.77 | HTR7 (0.65) | LMNAKMT2AMEN1GAANPY5R | |
| Hydrochloric Acid SCHEMBL9400405 | 0.76 | HTR7 (0.64) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9032918 | 0.74 | LMNA (0.56) | LMNAKMT2AMEN1GAANPY5R | |
| SCHEMBL9034060 | 0.74 | LMNA (0.56) | LMNAKMT2AMEN1GAANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442348-B1 | Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5356922-A | Treatment of disturbances in microcirculation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-5232922-A | Cardiovascular disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0442348-A2 | Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-21 | — | — | EP | disclosed |