Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL6407632 | 0.89 | GSK3B (0.75) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL28620529 | 0.89 | GSK3B (0.75) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL8370157 | 0.83 | GSK3B (0.71) | GSK3BCASP7CASP3CASP2CASP6 | |
| Anthraquinone SCHEMBL11096676 | 0.81 | NPC1 (0.59) | CASP3ACHECSNK1G1MEN1KMT2A | |
| Phthalimide SCHEMBL27537048 | 0.80 | GSK3B (0.60) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL11705794 | 0.80 | GSK3B (0.60) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL2261244 | 0.79 | GSK3B (0.65) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL1616990 | 0.78 | GSK3B (0.88) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL23063638 | 0.78 | GSK3B (0.88) | GSK3BCASP7CASP3CASP2CASP6 | |
| Phthalimide SCHEMBL64 | 0.78 | GSK3B (1.00) | GSK3BCASP7CASP3CASP2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | disclosed |