Phthalimide

Phthalimide

SCHEMBL28620529

Cc1ccc(C)cc1.O=C1NC(=O)c2ccccc21

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.75
CASP3 P42574 2/20 0.70
CASP7 P55210 2/20 0.70
CASP6 P55212 2/20 0.70
CASP8 Q14790 2/20 0.70
CASP2 P42575 1/20 0.70
CSNK1G1 Q9HCP0 1/20 0.53
TNKS2 Q9H2K2 1/20 0.53
ACVR1 Q04771 2/20 0.52
LRRK2 Q5S007 2/20 0.52
ROS1 P08922 1/20 0.52
CDK5 Q00535 1/20 0.52
EGFR P00533 1/20 0.52
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
PARP1 P09874 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
PDGFRA P16234 1/20 0.48
FER P16591 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL8370157 0.93 GSK3B (0.71) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL27368901 0.89 GSK3B (0.60) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11705794 0.89 GSK3B (0.60) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL23063638 0.87 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL30125197 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL64 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL10192661 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11040503 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL7771670 0.87 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402448-B Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof 中国船舶重工集团公司第七二五研究所 2023-03-17 CN disclosed
CN-113402448-A Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof 中国船舶重工集团公司第七二五研究所 2021-09-17 CN disclosed