Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12217560 | 0.83 | CREBBP (0.42) | MGLLCREBBPCA2HTTTYR | |
| SCHEMBL16118977 | 0.78 | MGLL (0.44) | MGLLCREBBPCA2LPLLIPG | |
| SCHEMBL24665804 | 0.77 | CREBBP (0.38) | CREBBPTYRPOLBMAPT | |
| SCHEMBL27973454 | 0.76 | MGLL (0.43) | MGLLCA2LPLLIPGPLK1 | |
| SCHEMBL22757235 | 0.73 | KCNH2 (0.38) | SIGMAR1 | |
| SCHEMBL21484163 | 0.73 | SIGMAR1 (0.33) | CREBBPHTTSIGMAR1ALDH1A1 | |
| SCHEMBL25659884 | 0.73 | ALDH1A1 (0.47) | MGLLHTTKDM4EALDH1A1POLB | |
| SCHEMBL19068792 | 0.73 | MAPT (0.49) | MGLLHTTKDM4EALDH1A1POLB | |
| SCHEMBL11983452 | 0.72 | ALDH1A1 (0.60) | CREBBPHTTKDM4EALDH1A1POLB | |
| SCHEMBL13283400 | 0.72 | POLB (0.40) | MGLLHTTTYRCNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059665-A1 | DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |