Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369779 | 0.87 | CA2 (0.36) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL27366224 | 0.86 | MEN1 (0.36) | MEN1KMT2AKDM4EATMEPHX2 | |
| SCHEMBL27369741 | 0.86 | MEN1 (0.36) | MEN1KMT2AKDM4EATMEPHX2 | |
| SCHEMBL21842292 | 0.84 | MEN1 (0.40) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL24572502 | 0.77 | PAOX (0.44) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL27366217 | 0.77 | KDM4E (0.36) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL22909028 | 0.77 | PAOX (0.44) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL27369781 | 0.77 | F2 (0.38) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL27249897 | 0.77 | EPHX2 (0.39) | MEN1KMT2AEPHX2SCN1ASCN2A | |
| SCHEMBL8145102 | 0.75 | TDP1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054954-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |