Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114605 | 0.75 | ALDH1A1 (0.38) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL27438117 | 0.74 | NPC1 (0.36) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL7821065 | 0.73 | CYP2C19 (0.42) | KMT2AALDH1A1PTPN1 | |
| SCHEMBL7267885 | 0.71 | CYP3A4 (0.54) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL3410274 | 0.69 | TSHR (0.48) | TAAR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL11636438 | 0.69 | TSHR (0.48) | TAAR1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL18626200 | 0.69 | ADH1B (0.47) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL1357621 | 0.68 | TSHR (0.43) | TAAR1ALDH1A1TSHRPTPN1 | |
| SCHEMBL9025685 | 0.68 | TSHR (0.43) | KMT2ATAAR1ALDH1A1TSHRPTPN1 | |
| SCHEMBL27501657 | 0.68 | CYP2C19 (0.45) | KMT2AALDH1A1TSHRPTPN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054598-C | Pharmacologically active hydrazine derivatives and processes for preparation thereof | NORVATIS CO (CH) | 2000-07-19 | — | — | CN | disclosed |
| CN-1068333-A | Has hydrazine analog derivative of pharmacologically active and preparation method thereof | CIBA GEIGY AG (CH) | 1993-01-27 | — | — | CN | disclosed |