Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27366224 | 0.88 | MEN1 (0.36) | MEN1KMT2AEPHX2MTNR1AMTNR1B | |
| SCHEMBL27369741 | 0.88 | MEN1 (0.36) | MEN1KMT2AEPHX2MTNR1AMTNR1B | |
| SCHEMBL27364923 | 0.86 | EPHX2 (0.37) | MEN1KMT2AEPHX2RECQLALDH1A1 | |
| SCHEMBL27364848 | 0.84 | MEN1 (0.38) | MEN1KMT2AEPHX2 | |
| SCHEMBL23190300 | 0.75 | MEN1 (0.58) | MEN1KMT2AEPHX2RECQL | |
| SCHEMBL12572605 | 0.75 | MEN1 (0.58) | MEN1KMT2AEPHX2RECQL | |
| SCHEMBL17145177 | 0.73 | MEN1 (0.61) | MEN1KMT2AEPHX2RECQLTSHR | |
| SCHEMBL27369636 | 0.73 | MEN1 (0.36) | MEN1KMT2AEPHX2ALDH1A1MTNR1A | |
| SCHEMBL27456337 | 0.73 | ALDH1A1 (0.34) | MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL27369779 | 0.72 | CA2 (0.36) | MEN1KMT2AEPHX2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054954-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |