Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805305 | 0.96 | ALDH1A1 (0.35) | ALDH1A1ECE1LMNASLC15A2HPGD | |
| SCHEMBL23253739 | 0.86 | PAOX (0.45) | ALDH1A1HPGDKMT2ASMN1; SMN2PAOX | |
| SCHEMBL23179898 | 0.83 | ALDH1A1 (0.38) | ALDH1A1ECE1LMNASLC15A2HPGD | |
| SCHEMBL23805304 | 0.82 | PAOX (0.38) | ALDH1A1HPGDKMT2ATP53SMN1; SMN2 | |
| SCHEMBL27370003 | 0.81 | PSMB5 (0.31) | ALDH1A1 | |
| SCHEMBL23253839 | 0.79 | CHRNB2 (0.34) | ECE1 | |
| SCHEMBL27266013 | 0.77 | ALDH1A1 (0.34) | ALDH1A1ECE1HPGDKMT2ATP53 | |
| SCHEMBL15071678 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1ECE1HPGDKMT2ATP53 | |
| SCHEMBL26740179 | 0.75 | FOLH1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27369995 | 0.74 | ECE1 (0.40) | ALDH1A1ECE1LMNASLC15A2PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024036329-A2 | CYTOTOXIC COMPOUNDS AND CONJUGATES THEREOF | SEAGEN INC. (US) | 2024-02-15 | — | — | WO | disclosed |