Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23179898 | 0.93 | ALDH1A1 (0.38) | ALDH1A1ECE1CYP1A2HPGDKMT2A | |
| SCHEMBL19302563 | 0.80 | ADRA1A (0.44) | ALDH1A1HPGDKMT2ATP53SMN1; SMN2 | |
| SCHEMBL27369997 | 0.77 | ALDH1A1 (0.33) | ALDH1A1ECE1HPGDKMT2ATP53 | |
| SCHEMBL15071678 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1ECE1PSMB5HPGDKMT2A | |
| SCHEMBL27266145 | 0.75 | LMNA (0.48) | ALDH1A1ECE1KMT2AFOLH1 | |
| SCHEMBL23805304 | 0.75 | PAOX (0.38) | ALDH1A1HPGDKMT2ATP53SMN1; SMN2 | |
| SCHEMBL23805305 | 0.75 | ALDH1A1 (0.35) | ALDH1A1ECE1HPGD | |
| SCHEMBL22987368 | 0.74 | CA1 (0.38) | ALDH1A1ECE1KMT2A | |
| SCHEMBL21888407 | 0.74 | GABRR1 (0.50) | ALDH1A1CYP1A2HPGDKMT2ATP53 | |
| SCHEMBL13071570 | 0.74 | CYP3A4 (0.42) | ALDH1A1CYP1A2HPGDKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110905-A1 | ANTI-CEA ANTIBODY DRUG CONJUGATES AND METHODS OF USE | BEIGENE, LTD. (KY) | 2024-05-30 | — | — | WO | disclosed |