Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GALR3 | O60755 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510673 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL24196743 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL8543977 | 0.76 | HTT (0.64) | MAPTSMN1; SMN2HTTLMNAMEN1 | |
| SCHEMBL8546280 | 0.76 | GALR3 (0.51) | MAPTHTTLMNAGALR3TP53 | |
| SCHEMBL8547776 | 0.75 | HTT (0.54) | MAPTALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL26255153 | 0.75 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL24197153 | 0.74 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL24196741 | 0.73 | HTT (0.54) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL8542136 | 0.73 | AURKA (0.48) | HTTLMNAGALR3MAPK1AURKA | |
| SCHEMBL8544656 | 0.73 | CCNC (0.55) | MAPTSMN1; SMN2HTTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | disclosed |