Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27371685 | 0.82 | MAPT (0.62) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7501246 | 0.78 | HTR1A (0.53) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7505610 | 0.78 | FERMT2 (0.46) | ALDH1A1SMN1; SMN2RAB9AMAPTHTR1A | |
| SCHEMBL7510138 | 0.77 | HTR1A (0.49) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7506038 | 0.77 | MAPT (0.48) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7502543 | 0.76 | CCNC (0.46) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7504497 | 0.76 | LMNA (0.56) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL23202861 | 0.75 | HTR1A (0.47) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL7505544 | 0.75 | HTR1A (0.54) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT | |
| SCHEMBL30827848 | 0.75 | HTR1A (0.47) | ALDH1A1SMN1; SMN2RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |