Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.35 |
| ▸ | CHKA | P35790 | 7/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661292 | 0.78 | CHKA (0.47) | KDM4EALDH1A1RAB9ACHKAMEN1 | |
| SCHEMBL18775290 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1RAB9ACHKA | |
| SCHEMBL2737184 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1RAB9ACHKACA2 | |
| SCHEMBL19696374 | 0.74 | CHKA (0.46) | KDM4EALDH1A1RAB9ACHKA | |
| SCHEMBL17384311 | 0.73 | CHKA (0.43) | KDM4EALDH1A1RAB9ACHKAMEN1 | |
| SCHEMBL10137237 | 0.72 | CHKA (0.36) | KDM4EALDH1A1RAB9ACHKA | |
| SCHEMBL13092015 | 0.72 | ENPP2 (0.55) | KDM4EALDH1A1RAB9ALPLLIPG | |
| SCHEMBL3784543 | 0.70 | LPL (0.50) | LPLLIPGCA2 | |
| SCHEMBL24044011 | 0.70 | CA1 (0.44) | KDM4EALDH1A1RAB9ACHKACA2 | |
| SCHEMBL12530382 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1RAB9ACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9757057-B2 | Dry insertion and one-point in vivo calibration of an optical analyte sensor | MEDTRONIC MINIMED, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9693720-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150080685-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | MEDTRONIC MINIMED, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8983565-B2 | Optical determination of pH and glucose | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8979790-B2 | Use of an equilibrium sensor to monitor glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140350364-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | CITIBANK, N.A. | 2014-11-27 | — | — | US | disclosed |
| US-8838195-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8738107-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20140128694-A1 | DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR | GLUMETRICS, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8473222-B2 | Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction | GLUMETRICS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120116191-A1 | USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL | GLUMETRICS, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-8088097-B2 | Use of an equilibrium intravascular sensor to achieve tight glycemic control | GLUMETRICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110224516-A1 | MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION | GLUMETRICS, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| US-20100274110-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | GluMetrics, Inc (US) | 2010-10-28 | — | — | US | disclosed |
| US-7751863-B2 | Optical determination of ph and glucose | GLUMETRICS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090177143-A1 | USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL | CITIBANK, N.A. | 2009-07-09 | — | — | US | disclosed |
| US-20090018418-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | GLUMETRICS, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080188725-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188722-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |