SCHEMBL2737196

SCHEMBL2737196

CC[n+]1cccc(-c2ccc[n+](CC)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
PKM P14618 1/20 0.51
APOBEC3A P31941 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
LMNA P02545 2/20 0.50
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CHRNA7 P36544 7/20 0.42
CHRNA10 Q9GZZ6 7/20 0.42
CHRNA9 Q9UGM1 7/20 0.42
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
GGPS1 O95749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28333949 0.93 LMNA (0.60) KDM4EPKMAPOBEC3AAPOBEC3GLMNA
SCHEMBL5953790 0.91 LMNA (0.48) KDM4EPKMAPOBEC3AAPOBEC3GLMNA
Bromide SCHEMBL10428847 0.91 LMNA (0.58) KDM4EPKMAPOBEC3AAPOBEC3GLMNA
SCHEMBL20524265 0.85 KDM4E (0.53) KDM4EPKMAPOBEC3AAPOBEC3GLMNA
SCHEMBL13177941 0.80 CYP1A2 (0.46) KDM4EPKMAPOBEC3AAPOBEC3GGGPS1
SCHEMBL294294 0.78
SCHEMBL29556923 0.78
SCHEMBL5028519 0.76
SCHEMBL7969197 0.76
Water SCHEMBL15375305 0.76 PABPC1 (0.47) KDM4EPKMAPOBEC3AAPOBEC3GLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839378-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2017-12-12 US disclosed
US-9757057-B2 Dry insertion and one-point in vivo calibration of an optical analyte sensor MEDTRONIC MINIMED, INC. (US) 2017-09-12 US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-8979790-B2 Use of an equilibrium sensor to monitor glucose concentration MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-20140350364-A1 OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION CITIBANK, N.A. 2014-11-27 US disclosed
US-8838195-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2014-09-16 US disclosed
US-8738107-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2014-05-27 US disclosed
US-20140128694-A1 DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR GLUMETRICS, INC. (US) 2014-05-08 US disclosed
US-8473222-B2 Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction GLUMETRICS, INC. (US) 2013-06-25 US disclosed
US-20120116191-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2012-05-10 US disclosed
US-8088097-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2012-01-03 US disclosed
US-20110224516-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION GLUMETRICS, INC. (US) 2011-09-15 US disclosed
US-20100274110-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE GluMetrics, Inc (US) 2010-10-28 US disclosed
US-7751863-B2 Optical determination of ph and glucose GLUMETRICS, INC. (US) 2010-07-06 US disclosed
US-20090177143-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL CITIBANK, N.A. 2009-07-09 US disclosed
US-20090018418-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT GLUMETRICS, INC. (US) 2009-01-15 US disclosed
US-20080188725-A1 OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION MEDTRONIC MINIMED, INC. 2008-08-07 US disclosed
US-20080188722-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE MEDTRONIC MINIMED, INC. 2008-08-07 US disclosed