SCHEMBL5953790

SCHEMBL5953790

CC[n+]1ccc(-c2ccc[n+](CC)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
KDM4E B2RXH2 2/20 0.46
PKM P14618 1/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
HTT P42858 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CHRNA7 P36544 8/20 0.41
CHRNA10 Q9GZZ6 8/20 0.41
CHRNA9 Q9UGM1 8/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2737196 0.91 KDM4E (0.51) LMNAKDM4EPKMAPOBEC3AAPOBEC3G
SCHEMBL28333949 0.89 LMNA (0.60) LMNAKDM4EPKMAPOBEC3AAPOBEC3G
Bromide SCHEMBL10428847 0.88 LMNA (0.58) LMNAKDM4EPKMAPOBEC3AAPOBEC3G
SCHEMBL7968644 0.82 SLC22A2 (0.54) LMNAKDM4EHTTRAB9ASMN1; SMN2
SCHEMBL1305882 0.82 MEN1 (0.54) LMNAKDM4EAPOBEC3AAPOBEC3GHTT
Bromide SCHEMBL9329150 0.80 SLC22A2 (0.52) LMNAKDM4EHTTRAB9ASMN1; SMN2
Iodide SCHEMBL7968992 0.80 SLC22A2 (0.52) LMNAKDM4EPKMAPOBEC3AAPOBEC3G
Iodide SCHEMBL3377972 0.79 KDM4E (0.56) LMNAKDM4EAPOBEC3AAPOBEC3GHTT
Hydrochloric Acid SCHEMBL17504837 0.79 MEN1 (0.52) LMNAKDM4EAPOBEC3AAPOBEC3GHTT
Bromide SCHEMBL483094 0.79 MEN1 (0.52) LMNAKDM4EHTTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839378-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2017-12-12 US disclosed
US-9757057-B2 Dry insertion and one-point in vivo calibration of an optical analyte sensor MEDTRONIC MINIMED, INC. (US) 2017-09-12 US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 US disclosed
US-8979790-B2 Use of an equilibrium sensor to monitor glucose concentration MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-20140350364-A1 OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION CITIBANK, N.A. 2014-11-27 US disclosed
US-8838195-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2014-09-16 US disclosed
US-8738107-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2014-05-27 US disclosed
US-20140128694-A1 DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR GLUMETRICS, INC. (US) 2014-05-08 US disclosed
US-20130287631-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION MEDTRONIC MINIMED, INC. 2013-10-31 US disclosed
US-8535262-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2013-09-17 US disclosed
US-8498682-B2 Optical determination of pH and glucose GLUMETRICS, INC. (US) 2013-07-30 US disclosed
US-8473222-B2 Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction GLUMETRICS, INC. (US) 2013-06-25 US disclosed
US-20120116191-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2012-05-10 US disclosed
US-20110224516-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION GLUMETRICS, INC. (US) 2011-09-15 US disclosed
US-20100274110-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE GluMetrics, Inc (US) 2010-10-28 US disclosed
US-7751863-B2 Optical determination of ph and glucose GLUMETRICS, INC. (US) 2010-07-06 US disclosed
US-20090018418-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT GLUMETRICS, INC. (US) 2009-01-15 US disclosed
US-20080188722-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE MEDTRONIC MINIMED, INC. 2008-08-07 US disclosed