Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835014 | 0.85 | MAPT (0.38) | LMNAPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1432767 | 0.85 | AOC3 (0.39) | LMNAPOLBGSRKMT2AMEN1 | |
| SCHEMBL4670361 | 0.82 | ALDH1A1 (0.37) | LMNAKMT2AMEN1SLC6A4SMN1; SMN2 | |
| SCHEMBL6003373 | 0.82 | POLB (0.42) | LMNAPOLBSLC6A4SMN1; SMN2SLC7A5 | |
| SCHEMBL5515058 | 0.81 | CYP17A1 (0.39) | LMNAPOLBKMT2ASLC6A4SMN1; SMN2 | |
| SCHEMBL3928059 | 0.80 | SLC7A5 (0.40) | LMNAPOLBSMN1; SMN2SLC7A5KDM4E | |
| SCHEMBL21632633 | 0.80 | LMNA (0.42) | LMNAMIFIGLV6-57KMT2AMEN1 | |
| SCHEMBL11480147 | 0.80 | GSR (0.37) | LMNAPOLBGSRKMT2ASLC6A4 | |
| SCHEMBL6716961 | 0.79 | ALDH1A1 (0.40) | POLBSMN1; SMN2SLC7A5ALDH1A1 | |
| SCHEMBL6723179 | 0.79 | ALDH1A1 (0.40) | POLBSMN1; SMN2SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112705-A1 | BORONIC ACID AND BORONATE COMPOSITIONS AND METHODS | ELIMA THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | claimed |
| EP-2758389-B1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | claimed |
| US-9394282-B2 | Pyrazole carboxamides as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-19 | — | — | US | claimed |
| US-20140235641-A1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | INTERVET INC. | 2014-08-21 | — | — | US | claimed |
| US-6762180-B1 | Substituted indolines which inhibit receptor tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-07-13 | — | — | US | claimed |
| EP-1206446-B1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-26 | — | — | EP | claimed |
| EP-1322608-A1 | DELTA1-PYRROLINES USED AS PESTICIDES | Bayer CropScience AG (DE) | 2003-07-02 | — | — | EP | claimed |
| WO-2002024646-A1 | DELTA1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-03-28 | — | — | WO | claimed |
| WO-2024112705-A1 | BORONIC ACID AND BORONATE COMPOSITIONS AND METHODS | ELIMA THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| US-20240156792-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-05-16 | — | — | US | disclosed |
| WO-2024075815-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | 国立大学法人大阪大学 | 2024-04-11 | — | — | WO | disclosed |
| US-11918562-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-03-05 | — | — | US | disclosed |
| WO-2024033845-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-15 | — | — | WO | disclosed |
| CN-113993719-B | Trisulfide compound | 住友化学株式会社 | 2024-01-02 | — | — | CN | disclosed |
| US-4220647-A | MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4108861-A | Azetothiazole-5-yl-3-halomethyl-2-butenoic acid derivatives and the preparation of 5-thia-1-azabicyclo-[4.2.0]-2-octene-2-carboxylic acid derivatives from them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| US-4057550-A | 14,15-DIHYDRO-14-CYANO-EBURNAMENINES, VASODILATION | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-11-08 | — | — | US | disclosed |
| US-4054571-A | Nitrogen-containing polycyclic compounds and a process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-10-18 | — | — | US | disclosed |
| US-3933859-A | BLOOD PRESSURE LOWERING, SYMPATHECTOMY | HOFFMANN-LA ROCHE, INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156792-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | HSP90AB1, HSP90AA1, HSP90AB2P | LMNA 4736/4885MIF 3740/4885IGLV6-57 4770/4885 |
| US-11918562-B2 | Combination therapy using azabicyclo compound for cancer | HSP90AB1, HSP90AA1, HSP90AB2P | LMNA 4736/4885MIF 3740/4885IGLV6-57 4770/4885 |
| US-20140235641-A1 | PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | JAK1, JAK3, JAK2 | LMNA 4840/4885MIF 948/4885IGLV6-57 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.