Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 9/20 | 0.33 |
| ▸ | F7 | P08709 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 7/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540174 | 0.78 | AKR1B1 (0.42) | MEN1MITFKMT2AGAAMAPT | |
| SCHEMBL27353793 | 0.67 | IDO1 (0.36) | MEN1KMT2A | |
| SCHEMBL11722555 | 0.59 | ALDH1A1 (0.43) | KMT2AGAAMAPTPDK2POLB | |
| SCHEMBL9539805 | 0.57 | PGR (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL18012748 | 0.57 | PDK2 (0.58) | MAPTPDK2 | |
| SCHEMBL9571265 | 0.57 | AKR1B1 (0.47) | MEN1MITFKMT2APDK2TSHR | |
| SCHEMBL18012639 | 0.57 | NPC1 (0.52) | KMT2AMAPTPDK2POLB | |
| Acetophenone SCHEMBL27469600 | 0.55 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTALOX15 | |
| Acetophenone SCHEMBL27977927 | 0.55 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTALOX15TSHR | |
| SCHEMBL19075863 | 0.55 | PDK2 (0.51) | MEN1KMT2AGAAMAPTCYBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071917-A | Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist | MERCK & CO INC (US) | 1993-05-12 | — | — | CN | disclosed |