Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364305 | 0.78 | IDO1 (0.33) | IDO1AKR1B1HTR7 | |
| SCHEMBL27372550 | 0.78 | MEN1 (0.34) | IDO1AKR1B1HTR7MEN1KMT2A | |
| SCHEMBL27373077 | 0.75 | AKR1B1 (0.33) | IDO1AKR1B1MEN1KMT2APGR | |
| SCHEMBL27372553 | 0.74 | AKR1B1 (0.33) | IDO1AKR1B1PGR | |
| SCHEMBL9539756 | 0.72 | AKR1B1 (0.56) | IDO1AKR1B1HTR7TGM2MEN1 | |
| SCHEMBL27357835 | 0.69 | PGR (0.35) | PGR | |
| SCHEMBL27373629 | 0.67 | F11 (0.33) | MEN1KMT2A | |
| SCHEMBL27458359 | 0.67 | PGR (0.48) | PGR | |
| SCHEMBL28775357 | 0.64 | HTR2C (0.33) | PGRCBX7CDYL2CDYLCDY1; CDY1B | |
| SCHEMBL28805368 | 0.62 | KDM4E (0.38) | IDO1TDO2TGM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071917-A | Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist | MERCK & CO INC (US) | 1993-05-12 | — | — | CN | disclosed |