SCHEMBL27373867

SCHEMBL27373867

Cc1cc(N)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.60
CYP1A2 P05177 1/20 0.60
MAPK1 P28482 5/20 0.56
ALDH1A1 P00352 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
CASP3 P42574 1/20 0.56
HBB P68871 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
MAOA P21397 2/20 0.55
MAOB P27338 1/20 0.55
ADORA2A P29274 5/20 0.53
CSNK1A1 P48729 2/20 0.53
CSNK1D P48730 2/20 0.53
CSNK1G1 Q9HCP0 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14608606 0.87 CYP1A1 (0.72) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL10813018 0.85 CYP1A1 (0.70) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL2256190 0.85 ADORA2A (0.53) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL12593738 0.81 CYP1A1 (0.55) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL30886455 0.80 ALDH1A1 (0.67) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL55743 0.80 ALDH1A1 (0.67) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL6273633 0.79 ADORA2A (0.79) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL13286975 0.78 GNG2 (0.59) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL10750755 0.78 ALDH1A1 (0.60) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2
SCHEMBL27749669 0.78 CYP1A1 (0.70) CYP1A1CYP1A2MAPK1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1052043-A 2-PART HAIR DYEING AGENTS SUNSTAR KK (JP) 1991-06-12 CN disclosed