Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094273 | 0.93 | TDP1 (0.69) | TDP1TP53NPC1RAB9AGAA | |
| SCHEMBL23094207 | 0.85 | TDP1 (0.78) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL9809465 | 0.84 | TDP1 (0.66) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL27374018 | 0.83 | MAPT (0.78) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL23094277 | 0.82 | TDP1 (1.00) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL27374100 | 0.80 | NPC1 (0.66) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL27374013 | 0.80 | SMN1; SMN2 (0.61) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL27374173 | 0.80 | LMNA (0.57) | TDP1TP53NPC1RAB9AGAA | |
| SCHEMBL27374087 | 0.79 | RAB9A (0.63) | TDP1NPC1RAB9AGAANFKB1 | |
| SCHEMBL23094291 | 0.79 | TP53 (1.00) | TDP1TP53MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031002-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2024-02-08 | — | — | WO | disclosed |