Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357995 | 0.95 | TXNRD1 (0.37) | TXNRD1MAPTPOLBALDH1A1LMNA | |
| SCHEMBL27371460 | 0.95 | TXNRD1 (0.35) | TXNRD1MAPTSLC9A1VCAM1MCOLN3 | |
| SCHEMBL27372102 | 0.94 | TXNRD1 (0.37) | TXNRD1MAPTPOLBALDH1A1LMNA | |
| SCHEMBL27531434 | 0.86 | TXNRD1 (0.34) | TXNRD1MAPTMCOLN3ALDH1A1LMNA | |
| SCHEMBL6938291 | 0.86 | SLC9A1 (0.52) | SLC9A1 | |
| SCHEMBL27375865 | 0.84 | MAPT (0.34) | MAPTVCAM1MCOLN3ALDH1A1LMNA | |
| SCHEMBL8542808 | 0.84 | TXNRD1 (0.37) | TXNRD1MAPTVCAM1MCOLN3TSHR | |
| SCHEMBL27374122 | 0.83 | SLC9A1 (0.47) | MAPTSLC9A1VCAM1POLBHTT | |
| SCHEMBL6933357 | 0.81 | SLC9A1 (0.50) | SLC9A1 | |
| SCHEMBL6938035 | 0.81 | SLC9A1 (0.50) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071743-C | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
| CN-1148590-A | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 1997-04-30 | — | — | CN | disclosed |