Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543171 | 0.95 | TXNRD1 (0.39) | TXNRD1MAPTVCAM1MCOLN3TSHR | |
| SCHEMBL8542221 | 0.95 | TXNRD1 (0.41) | TXNRD1MAPTVCAM1MCOLN3GSR | |
| SCHEMBL8538162 | 0.94 | TXNRD1 (0.41) | TXNRD1MAPTGSRPOLBALDH1A1 | |
| SCHEMBL8538600 | 0.94 | TXNRD1 (0.41) | TXNRD1MAPTGSRPOLBALDH1A1 | |
| SCHEMBL8542635 | 0.85 | TXNRD1 (0.36) | TXNRD1MAPTVCAM1MCOLN3GSR | |
| SCHEMBL27375129 | 0.84 | TXNRD1 (0.35) | TXNRD1MAPTVCAM1MCOLN3TSHR | |
| SCHEMBL8538637 | 0.83 | MAPT (0.35) | MAPTVCAM1MCOLN3POLBALDH1A1 | |
| SCHEMBL8538826 | 0.82 | VCAM1 (0.49) | MAPTVCAM1TSHRPOLBPDGFRB | |
| SCHEMBL6938291 | 0.82 | SLC9A1 (0.52) | — | |
| SCHEMBL8543278 | 0.80 | TXNRD1 (0.38) | TXNRD1MAPTVCAM1MCOLN3GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |