Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971997 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1LMNA | |
| SCHEMBL27347730 | 0.75 | KMT2A (0.44) | PTPN1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10370914 | 0.72 | TSHR (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9548337 | 0.72 | CPA3 (0.56) | MME | |
| SCHEMBL3024154 | 0.72 | CA12 (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8765867 | 0.70 | CYP1A2 (0.47) | MMEMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL9544466 | 0.70 | CYP1A2 (0.47) | MMEMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL5039697 | 0.70 | PTPN1 (0.54) | PTPN1KDM4EALDH1A1LMNA | |
| SCHEMBL22077887 | 0.68 | TSHR (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL9456168 | 0.68 | PTPN1 (0.55) | PTPN1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040747-C | N-substituting group-4-substituted benzyl-5-alkyl-5-substituted benzyl-pyrrolidone-2, and its intermediate, its synthetic method and its appliance | KUNMING PLANT INST CHINESE ACA (CN) | 1998-11-18 | — | — | CN | disclosed |
| CN-1120036-A | N-substituting group-4-substituted benzyl-5-alkyl-5-substituted benzyl-pyrrolidone-2, and its intermediate, its synthetic method and its appliance | KUNMING PLANT INST CHINESE ACA (CN) | 1996-04-10 | — | — | CN | disclosed |