SCHEMBL27375417

SCHEMBL27375417

CCC(=O)ONC(N)=O.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
NAAA Q02083 1/20 0.32
TSHR P16473 3/20 0.32
CRBN Q96SW2 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
NFKB1 P19838 2/20 0.30
FFAR3 O14843 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27353580 0.97
SCHEMBL28265511 0.81 TAS2R38 (0.36) ALDH1A1ALOX15MGAMGAASI
SCHEMBL583206 0.80
SCHEMBL13268373 0.79
SCHEMBL13734020 0.78 TSHR (0.37) MGAMGAASIMGAM2TSHR
Iodide SCHEMBL29117518 0.78 ALOX15 (0.33) ALDH1A1ALOX15MGAMGAASI
SCHEMBL27781159 0.78
SCHEMBL3804877 0.78 ALDH1A1 (0.50) ALDH1A1ALOX15MGAMGAASI
SCHEMBL4897752 0.77 KMT2A (0.39) ALDH1A1ALOX15MGAMGAASI
SCHEMBL5037696 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109047985-A A kind of hard solid watchcase manufacture craft of gold of link fuse 3D 福州珂麦表业有限公司 2018-12-21 CN disclosed
CN-1043125-A Be used as the aryl urea of the replacement of high-potency sweetener NUTRASWEET CO (US) 1990-06-20 CN disclosed