Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383032 | 0.76 | GABRA1 (0.34) | LTA4H | |
| SCHEMBL27383034 | 0.76 | LTA4H (0.46) | LTA4HALDH1A1KDM4EARTDP1 | |
| SCHEMBL15637377 | 0.73 | IDO1 (0.48) | LTA4HIDO1ALDH1A1KDM4EATM | |
| SCHEMBL23144898 | 0.72 | IDO1 (0.49) | LTA4HIDO1ALDH1A1KDM4EATM | |
| SCHEMBL27501099 | 0.72 | LTA4H (0.42) | LTA4HIDO1ALDH1A1KDM4EATM | |
| SCHEMBL23960285 | 0.70 | MPL (0.32) | POLBMPL | |
| Hydrochloric Acid SCHEMBL23927267 | 0.69 | MPL (0.31) | IDO1POLBMPL | |
| SCHEMBL22231732 | 0.69 | IDO1 (0.41) | LTA4HIDO1ALDH1A1KDM4EATM | |
| SCHEMBL1861219 | 0.68 | IDO1 (0.43) | LTA4HIDO1ALDH1A1KDM4EATM | |
| SCHEMBL22231996 | 0.68 | IDO1 (0.41) | LTA4HIDO1ALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081638-C | Thienopyrimidine compounds | MERCK PATENT GMBH (DE) | 2002-03-27 | — | — | CN | disclosed |
| CN-1227560-A | Thienopyrimidines | MERCK PATENT GMBH (DE) | 1999-09-01 | — | — | CN | disclosed |