Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377635 | 0.72 | LTA4H (0.48) | LTA4HIDO1EGFRARKDM4E | |
| SCHEMBL9831326 | 0.66 | ALDH1A1 (0.51) | KMT2AF2F10KDM4EALDH1A1 | |
| SCHEMBL28206568 | 0.66 | CYP19A1 (0.53) | IDO1KMT2AP2RX7KDM4EALDH1A1 | |
| SCHEMBL23144898 | 0.63 | IDO1 (0.49) | LTA4HIDO1EGFRARKMT2A | |
| SCHEMBL27404925 | 0.60 | CYP11B1 (0.45) | LTA4HIDO1KMT2AALDH1A1LMNA | |
| SCHEMBL3727774 | 0.59 | ALDH1A1 (0.54) | LTA4HIDO1ARALDH1A1ATM | |
| SCHEMBL31061820 | 0.59 | GAA (0.44) | KDM4EALDH1A1LMNA | |
| SCHEMBL994006 | 0.59 | GAA (0.44) | KDM4EALDH1A1LMNA | |
| SCHEMBL15637377 | 0.58 | IDO1 (0.48) | LTA4HIDO1ARP2RX7KDM4E | |
| SCHEMBL3249477 | 0.58 | IDO1 (0.48) | LTA4HIDO1ARKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1227560-A | Thienopyrimidines | MERCK PATENT GMBH (DE) | 1999-09-01 | — | — | CN | disclosed |