Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31456977 | 0.91 | MKNK1 (0.42) | JAK2NTRK1MKNK1MKNK2JAK1 | |
| SCHEMBL21174101 | 0.86 | PIK3CD (0.41) | NTRK1METALK | |
| Hydrochloric Acid SCHEMBL21174087 | 0.85 | LOXL2 (0.42) | NTRK1METALK | |
| SCHEMBL27377996 | 0.77 | MKNK1 (0.41) | JAK2NTRK1MKNK1MKNK2JAK1 | |
| SCHEMBL30751335 | 0.77 | MKNK1 (0.41) | JAK2NTRK1MKNK1MKNK2JAK1 | |
| Trifluoroacetic Acid SCHEMBL31456989 | 0.76 | ACHE (0.46) | MET | |
| Trifluoroacetic Acid SCHEMBL31457031 | 0.75 | ACHE (0.46) | MET | |
| SCHEMBL21174253 | 0.73 | LOXL2 (0.52) | NTRK1METALK | |
| SCHEMBL1951909 | 0.72 | JAK2 (0.50) | JAK2MKNK1MKNK2JAK1JAK3 | |
| Hydrochloric Acid SCHEMBL21174133 | 0.72 | LOXL2 (0.53) | NTRK1METALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |