Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MET | P08581 | 15/20 | 0.42 |
| ▸ | FLT3 | P36888 | 5/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31457031 | 0.99 | ACHE (0.46) | ACHEMETFLT3AURKAMST1R | |
| Trifluoroacetic Acid SCHEMBL31456977 | 0.87 | MKNK1 (0.42) | METFLT3AURKAMST1RPIM1 | |
| SCHEMBL21174101 | 0.85 | PIK3CD (0.41) | METPIM1PIM2GSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL21174087 | 0.84 | LOXL2 (0.42) | METPIM1PIM2GSK3BDYRK1A | |
| Trifluoroacetic Acid SCHEMBL31457063 | 0.76 | LOXL2 (0.44) | METPIM1PIM2GSK3BDYRK1A | |
| SCHEMBL27378010 | 0.76 | JAK2 (0.46) | MET | |
| SCHEMBL31456943 | 0.75 | JAK2 (0.41) | ACHEMETGSK3BDYRK1A | |
| SCHEMBL27377918 | 0.75 | JAK2 (0.41) | ACHEMETGSK3BDYRK1A | |
| SCHEMBL31456978 | 0.74 | JAK2 (0.40) | ACHEMETGSK3BDYRK1A | |
| SCHEMBL27377968 | 0.74 | JAK2 (0.40) | ACHEMETGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |