SCHEMBL27379751

SCHEMBL27379751

CC#CCCc1cc[c]cc1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919310 0.79 GRM5 (0.49) GRM5KCNH2
SCHEMBL5702881 0.79
SCHEMBL8041091 0.76 PYCR1 (0.36) KCNH2
SCHEMBL8042787 0.76 PYCR1 (0.52)
SCHEMBL6576818 0.74 GFER (0.40) MEN1KMT2AKCNH2
SCHEMBL242001 0.73 MEN1 (0.56) MEN1KMT2A
SCHEMBL5702908 0.71 MEN1 (0.33) MEN1KMT2A
SCHEMBL17731 0.70
SCHEMBL8029213 0.70 ACACB (0.44) KCNH2
SCHEMBL11803736 0.69 MAOA (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100350968-C Modification of feeding behavior IMP COLLEGE INNOVATIONS LTD (GB) 2007-11-28 CN disclosed
CN-1596119-A Modification of feeding behavior IMP COLLEGE INNOVATIONS LTD (GB) 2005-03-16 CN disclosed
CN-1168711-C Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use �ϼ��������Ǵ�ѧ 2004-09-29 CN disclosed
CN-1350519-A Reversible aqueous pH Sensitive lipidizing reagents, compositions and methods of use UNIV SOUTHERN CALIFORNIA (US) 2002-05-22 CN disclosed
CN-1070487-C Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO CO (JP) 2001-09-05 CN disclosed