Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086869 | 0.89 | PDK1 (0.62) | MEN1KMT2APOLBRAB9AHDAC2 | |
| SCHEMBL14086870 | 0.89 | PDK1 (0.62) | MEN1KMT2APOLBRAB9AHDAC2 | |
| SCHEMBL8866262 | 0.87 | ABCC9 (0.68) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL8865957 | 0.79 | ABCC9 (0.69) | MEN1KMT2AABCC9ABCC8KCNJ11 | |
| SCHEMBL14715847 | 0.78 | PTPN1 (0.84) | MEN1KMT2APOLBPTPN1CACNA1B | |
| SCHEMBL8321463 | 0.76 | PDK1 (0.61) | MEN1KMT2ALMNARAB9AHDAC2 | |
| SCHEMBL11124245 | 0.76 | MEN1 (0.83) | MEN1KMT2APOLBPTPN1CACNA1B | |
| SCHEMBL30994891 | 0.76 | KCNK9 (0.72) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL26953087 | 0.76 | PTPN1 (0.88) | MEN1KMT2APOLBPTPN1CACNA1B | |
| SCHEMBL1315526 | 0.76 | PTPN1 (0.87) | MEN1KMT2APOLBPTPN1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069727-A | The acid amides that is used for the treatment of | ICI PLC (GB) | 1993-03-10 | — | — | CN | disclosed |