Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385036 | 0.86 | RAB9A (0.43) | RAB9AMTNR1AMTNR1BSMN1; SMN2IDH1 | |
| SCHEMBL27385039 | 0.85 | RAB9A (0.42) | RAB9AMTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL27385399 | 0.84 | PKM (0.47) | RAB9ASMN1; SMN2HPGDALDH1A1GAA | |
| SCHEMBL27385164 | 0.83 | RAB9A (0.41) | RAB9AMTNR1AMTNR1BSMN1; SMN2HTT | |
| SCHEMBL27384178 | 0.82 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2HPGDHTTPOLB | |
| SCHEMBL27383268 | 0.82 | RAB9A (0.61) | RAB9AMTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL27383728 | 0.82 | RAB9A (0.53) | RAB9AMTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL27384491 | 0.80 | SMN1; SMN2 (0.43) | RAB9AMTNR1AMTNR1BSMN1; SMN2HTT | |
| SCHEMBL27382675 | 0.80 | MTNR1A (0.44) | RAB9AMTNR1AMTNR1BSMN1; SMN2HPGD | |
| SCHEMBL27383947 | 0.79 | RAB9A (0.55) | RAB9AMTNR1AMTNR1BSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |