Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 6/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 2/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30920444 | 0.87 | RAB9A (0.43) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL27247588 | 0.87 | RAB9A (0.38) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL27246917 | 0.87 | RAB9A (0.43) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL30920136 | 0.87 | RAB9A (0.38) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL27384013 | 0.86 | RAB9A (0.39) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL27383517 | 0.86 | SMN1; SMN2 (0.42) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL30920545 | 0.86 | RAB9A (0.42) | RAB9ANPC1METTL3METTL14SMN1; SMN2 | |
| SCHEMBL30920207 | 0.84 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL27246962 | 0.84 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL30920135 | 0.83 | RAB9A (0.43) | RAB9ANPC1METTL3METTL14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |