SCHEMBL30920135

SCHEMBL30920135

COC(=O)c1cc2[nH]c(CNC(=O)C3(C)CC3)cc2cc1F

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ BDKRB1 P46663 3/20 0.33
▸ MTNR1A P48039 6/20 0.32
▸ MTNR1B P49286 5/20 0.32
▸ METTL3 Q86U44 5/20 0.31
▸ METTL14 Q9HCE5 5/20 0.31
▸ METAP2 P50579 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247881 1.00 RAB9A (0.43) RAB9ANPC1SMN1; SMN2BDKRB1MTNR1A
SCHEMBL27247120 0.88 SMN1; SMN2 (0.46) RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B
SCHEMBL30920614 0.88 SMN1; SMN2 (0.46) RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B
SCHEMBL27246962 0.85 RAB9A (0.41) RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B
SCHEMBL30920207 0.85 RAB9A (0.41) RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B
SCHEMBL27246917 0.84 RAB9A (0.43) RAB9ANPC1SMN1; SMN2METTL3METTL14
SCHEMBL30920444 0.84 RAB9A (0.43) RAB9ANPC1SMN1; SMN2METTL3METTL14
SCHEMBL30920545 0.83 RAB9A (0.42) RAB9ANPC1SMN1; SMN2METTL3METTL14
SCHEMBL27383632 0.83 RAB9A (0.42) RAB9ANPC1SMN1; SMN2BDKRB1MTNR1A
SCHEMBL27383275 0.77 EIF4A3 (0.47) RAB9ANPC1SMN1; SMN2METTL3METTL14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
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