SCHEMBL30920545

SCHEMBL30920545

CC1(C(=O)NCc2cc3cc(F)c(Br)cc3[nH]2)CC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 2/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MEN1 O00255 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ METTL3 Q86U44 7/20 0.32
▸ METTL14 Q9HCE5 7/20 0.32
▸ METAP2 P50579 3/20 0.31
▸ IKBKB O14920 1/20 0.30
▸ RET P07949 1/20 0.30
▸ FGFR1 P11362 1/20 0.30
▸ FGFR2 P21802 1/20 0.30
▸ FGFR3 P22607 1/20 0.30
▸ APOL1 O14791 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27246917 0.87 RAB9A (0.43) RAB9ANPC1SMN1; SMN2METTL3METTL14
SCHEMBL27247917 0.87 SMN1; SMN2 (0.38) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL30920444 0.87 RAB9A (0.43) RAB9ANPC1SMN1; SMN2METTL3METTL14
SCHEMBL30946188 0.87 RAB9A (0.39) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL27383632 0.86 RAB9A (0.42) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL27246821 0.85 RAB9A (0.36) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL30920251 0.84 SMN1; SMN2 (0.38) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL27247646 0.84 SMN1; SMN2 (0.38) RAB9ANPC1SMN1; SMN2MEN1LMNA
SCHEMBL30920207 0.84 RAB9A (0.41) RAB9ANPC1SMN1; SMN2
SCHEMBL27246922 0.84 MTNR1A (0.42) RAB9ANPC1SMN1; SMN2MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 RAB9A 105/4885NPC1 102/4885SMN1; SMN2 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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