Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GMNN | O75496 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124665 | 0.84 | CYP1A2 (0.40) | MEN1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL20581480 | 0.83 | ALDH1A1 (0.44) | FFAR3MEN1KMT2AMMP1MMP2 | |
| SCHEMBL4362567 | 0.83 | ALDH1A1 (0.44) | FFAR3MEN1KMT2AMMP1MMP2 | |
| SCHEMBL13576868 | 0.82 | MMP1 (0.55) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4361342 | 0.82 | MMP1 (0.36) | MEN1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL13335489 | 0.81 | ELANE (0.37) | MEN1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL15489098 | 0.80 | TSHR (0.39) | MEN1KMT2ACYP2C19RECQLMMP1 | |
| SCHEMBL1125336 | 0.80 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2510667 | 0.80 | MMP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL9300191 | 0.80 | TSHR (0.43) | CYP2C19MMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088365-B2 | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution | NEKTAR THERAPEUTICS (US) | 2012-01-03 | — | — | US | disclosed |
| US-7655747-B2 | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution | NEKTAR THERAPEUTICS (US) | 2010-02-02 | — | — | US | disclosed |
| WO-2008033352-A2 | MONOCARBOXYLATES FOR MODIFYING MACROPHAGE FUNCTION | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2008-03-20 | — | — | WO | disclosed |