Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.32 |
| ▸ | HTR3B | O95264 | 3/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451563 | 0.79 | LMNA (0.41) | LMNACYP2C9HTR3EHTR3BHTR3A | |
| SCHEMBL8268323 | 0.79 | CHRNB2 (0.46) | LMNACYP2C9HTR3EHTR3BHTR3A | |
| SCHEMBL25260782 | 0.77 | LMNA (0.44) | LMNACYP2C9HTR3EHTR3BHTR3A | |
| SCHEMBL21891883 | 0.76 | CHRNB2 (0.50) | CHRNA7TSHRHSD11B1ALDH1A1 | |
| SCHEMBL18820470 | 0.74 | LMNA (0.37) | LMNACYP2C9CHRNA7MEN1KMT2A | |
| SCHEMBL21891884 | 0.72 | ALDH1A1 (0.48) | LMNACYP2C9MEN1CYP2D6KMT2A | |
| SCHEMBL7037599 | 0.72 | LMNA (0.35) | LMNACYP2C9HTR3EHTR3BHTR3A | |
| SCHEMBL24543360 | 0.72 | LMNA (0.35) | LMNACYP2C9 | |
| SCHEMBL15632468 | 0.71 | CHRNB2 (0.43) | LMNACYP2C9CHRNA7TDP1MAPK1 | |
| SCHEMBL8374384 | 0.71 | CHRNB2 (0.38) | LMNACYP2C9CHRNA7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130105-A1 | CYCLOOCTENE COMPOSITIONS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-06-20 | — | — | WO | disclosed |