Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910780 | 0.76 | PTGS2 (0.41) | PTGS2CYP2A6NPC1CASP3ALDH1A1 | |
| SCHEMBL29892442 | 0.73 | MEN1 (0.55) | DHODHNPC1RAB9APTPN5ALDH1A1 | |
| SCHEMBL20829312 | 0.69 | DHODH (0.53) | DHODHNPC1CASP3RAB9ASENP8 | |
| SCHEMBL30278454 | 0.68 | NPC1 (0.50) | CYP2A6NPC1RAB9AALDH1A1MAPT | |
| P-Xylene SCHEMBL1420077 | 0.67 | ACHE (0.53) | DHODHNPC1RAB9APTPN5ALDH1A1 | |
| SCHEMBL598796 | 0.66 | ACHE (0.57) | DHODHNPC1RAB9APTPN5ALDH1A1 | |
| SCHEMBL29629004 | 0.65 | TDP1 (0.58) | CYP2A6PTPN5ALDH1A1MAPT | |
| SCHEMBL23003863 | 0.65 | ACHE (0.55) | DHODHNPC1RAB9APTPN5ALDH1A1 | |
| SCHEMBL5545442 | 0.65 | ACHE (0.55) | DHODHNPC1RAB9APTPN5ALDH1A1 | |
| SCHEMBL29929976 | 0.65 | ACHE (0.55) | DHODHNPC1RAB9APTPN5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097855-A2 | IDENTIFICATION OF SMALL MOLECULES THAT RECRUIT AND ACTIVATE RNASE L | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-05-10 | — | — | WO | disclosed |